Tuesday, January 27, 2009
Monday, January 26, 2009
Saturday, January 24, 2009
INKHEART TODAYY! Not bad la. Quite draggy, and not as funny as bedtime stories. Changeling is the nicest! Watched with Karen, Pei Xian and Eunice! *Loves! Karen bought couple seats, and deprived 2 couples of couple seats -.- No difference lor. She go in and pull down the arm rest -.-
Gymed today and I feel all weak and lousy now. Dunno why. heh
Wednesday, January 21, 2009
The wart!
There is currently no cure or treatment for HPV infection. (ZOMG)
It is estimated that 7-10% of the US population is infected. (Wow. Thats like 2.1 million to 3 million people. BROTHERS!) Infection typically occurs on moist walking surfaces such as showers, swimming pools, or shoes. (DAMN. No more swimming) The virus can survive many months without a host, making it highly contagious.
Because plantar warts are spread by contact with moist walking surfaces, they can be prevented by not walking barefoot in public areas such as showers or communal changing rooms, not sharing shoes and socks, and avoiding direct contact with warts on other parts of the body or on other people. (So uhhhh... Don't touch my foot, kaes. Right foot.) Humans build immunity with age, so infection is less common among adults than children. (Seeee uncle. I'm still young. Children.)
Once a person is infected, there is no evidence that any treatment eliminates HPV infection or decreases infectivity, and warts may recur after treatment because of activation of latent virus present in healthy skin adjacent to the lesion. There is currently no vaccine for these types of the virus. However, treatments are sometimes effective at addressing symptoms and causing remission (inactivity) of the virus.
Hahaha. Okay la. I got scared when I read it at first cause I thought this thing was like... no sweat man! So its more serious than I thought eh? Maybe I should tell the ns doctor and get him to de-pes me. hahaha!
The HPV lifecycle strictly follows the differentiation program of the host keratinocyte. It is thought that the HPV virion infects epithelial tissues through micro-abrasions, whereby the virion associates with putative receptors such as alpha integrins and laminins, leading to entry of the virions into basal epithelial cells through clathrin-mediated endocytosis and/or caveolin-mediated endocytosis depending on the type of HPV. At this point, the viral genome is transported to the nucleus by unknown mechanisms and establishes itself at a copy number between 10-200 viral genomes per cell. A sophisticated transcriptional cascade then occurs as the host keratinocyte begins to divide and become increasingly differentiated in the upper layers of the epithelium. The viral oncogenes, E6 and E7, are thought to modify the cell cycle so as to retain the differentiating host keratinocyte in a state that is amiable to the amplification of viral genome replication and consequent late gene expression. E6 in association with host E6 AP (associated protein), which has ubiquitin ligase activity act to ubiquitinate p53 leading to its proteosomal degradation. E7 (inoncogenic HPV's) acts as the primary transforming protein. E7 competes for pRb binding, freeing the transcription factor E2F to transactivate its targets, thus pushing the cell cycle forwards. All HPV can induce transient proliferation, but only 16 and 18 can immortalise cell intes (in vitro). It has also been shown that HPV 16 and 18 cannot immortalise primary rat cells alone, there needs to be activation of the ras oncogene. In the upper layers of the host epithelium, the late genes L1 and L2 are transcribed/translated and serve as structural proteins which encapsidate (Encapsidation is the process of incorporating a nucleic acid sequence (e.g., a vector, or a viral genome) into a viral particle) the amplified viral genomes. Virions can then be sloughed off in the dead squames of the host epithelium and the viral lifecycle continues.
@.@
Someone get me a panadol. Fast.
Monday, January 19, 2009
A-Famosa. Portugese Fort. These are some gravestones dating back to perhaps the 15th or 16th century. This place is SUPER COOL for a history fanatic like me
Eating spree over there! Ate this chicken rice ball. niceee! Summore its so cheap. One person convert to Sing dollars only 88 cents. CHEAP OR WHAT. 1 whole chicken summore for 9 people.
Friday, January 16, 2009
Wednesday, January 14, 2009
Saturday, January 10, 2009
Sunghun...
After that went for a haircut and then out to meet uncle at dhoby. Basket. I spent 71 cents to walk from on side of dhoby to the other. Ate at astons! The grilled fish with herb was not as nice as teh hickory bbq chicken, and stupid uncle poured chilli over my half eaten mashed potatoes. Left them there lo. Bo bian. So disgusting la. Bought tickets for 3.30 Bedtime Stories at the Cathay, but then Huiyi was late. Bedtime stories... okay la. Its not that nice a show. Some funny parts. Its like the less interesting version of Bolt. Walked to esplanade after the movie, took pictures!
Left uncle at Raffles and headed to the airport with Huiyi to send Sung off! Missed Tanah Merah and we sat to Simei before realising that we forgot to get off at Tanah Merah. My goodness. He's going back to Korea for don't know how many donkey months/years. Probably coming back next yr. Hais. What to do huh. Trained back with Huiyi. =)
ALL THE BEST SUNG!
Wednesday, January 07, 2009
The Bank Robber
The notes at the front and the back of the stack was real (correction. saw the news again and apparently the top and bottom notes are fake. they just look real), but there was nothing but blank slips of paper in between. Moreover, such notes are often traceable in the event of bank robberies.
hahahaha.
Tuesday, January 06, 2009
The post with (or without) Jasmine's widom teeth
KC accompanied me to the doctors today. He doesnt get up so early usually so kudos to him! =) The doctor gave me some antibiotics to eat. Tastes disgusting as usual. Went to eat KFC breakfast. Totally cmi man. The hashbrown was so bad that it cannot be described. The honey biscuit, chicken and egg were okay, but the chicken and egg so small! How to feed us! Summore is costs 6 bucks. zzz
went to shop for Janis's present, then went to Kc's house to rot. Played GTA! Left after lunch, and have been home ever since.
Jasmine got all 4 of her wisdom teeth plucked out today. She was still bleeding the last time I smsed her. Can only drink porridge and cant cew anything. haha. Poor thing. Get well soon!
Monday, January 05, 2009
Friday, January 02, 2009
Went to Lavender to get extra Army stuff. The store was okay, lots of stuff, well organised etc. But one of the sales ppl srsly blur like.. walao. I ask for one thing, she will repeat in my face with the blur look, then go and ask the shop keeper what it is I'm looking for. Didnt get to eat my curry chicken noodles today again. So headed over to Bugis, saw some nice shorts but didnt buy. Next time then buy, then headed home =)
So at night, got the news that I'M NOT GOING TO JAPAN. Blardy tour agency said tt not enough ppl so cancelled. Okay nvm. Then i tried to install a game kc lent me. Cnt install. Try to dwl, the game cnt work. Then to top it off I BIT INTO A FLY. I was eating smth and then i bit into smth hard. Spit it out and WALA! 2 WINGS.
BLAH.
Lucky got kaka cheer me up =) Thanks kaka!